Colon and rectal cancer are more frequently observed and diagnosed among people of age 65 to 74 years (median age is 68 years), though lately, it is visible in the lower age groups also. In the western world, colon cancer is observed more commonly than rectal cancer. In India, rectal cancer is more common with men being commonly affected than women.

Best Colorectal Cancer Doctors say that Colorectal cancer usually starts in the innermost layer (mucosa) and will grow through some or all of the tissue layers that make up the colon and rectum (submucosa, muscularis and serosa ). The extent to which a cancer penetrates the various tissue layers determines the stage of the disease.